Kawagishi T#, Sanchez-Tacuba L, Feng N, Greenberg HB#, and Ding S#. (2024) Comparative analysis of replication and virulence of wild-type and cell culture-adapted murine rotavirus VP4 by reverse genetics. Viruses. doi.org/10.3390/v16050767. # co-corresponding authors

Antia A, Alvarado DM, Zeng Q, Carsola-Perez LA, Davis DL, Sonnek NM, Ciorba MA#, and Ding S#. (2024) SARS-CoV-2 Omicron BA.1 variant infection of human colon epithelial cells. # co-corresponding authors. Viruses. Apr 19;16(4):634.

Qiao W, Richards CM, Kim Y, Zengel JR, Alonso MA, Ding S, Greenberg HB, and Carette JE. (2024) MYADM is a receptor essential for entry of human parechoviruses. Nat Commun. Apr 24;15(1):3469.

Zeng Q, Antia A, Carsola-Perez LA, Puray-Chavez Maritza, Kutluay SB, Ciorba MA, and Ding S. (2024) Calpain-2 regulates cell surface ACE2 levels and mediates SARS-CoV-2 entry. mBio. Feb 13:e0228723.

Xia M, Huang P, Vago FS, Kawagishi T, Ding S, Greenberg HB, Jiang W, and Tan M. (2024) A VP4-based trivalent pseudovirus nanoparticle vaccine elicited high and broad immune responses and protective immunity against the predominant P[8], P[4], and P[6] rotaviruses. ASC Nano. Feb 27;18(8):6673-6689.

Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, and Zhu S. (2024) A mouse model to distinguish NLRP6 mediated inflammasome-dependent and independent functions. Proc Natl Acad Sci U S A. Feb 6;121(6):e2321419121.

Matta SK, Kohio HP, Chandra P, Brown A, Doench JG, Philips JA, Ding S, and Sibley LD. (2024) Genome-wide and targeted CRISPR screens identify RNF213 as a mediator of interferon gamma-dependent pathogen restriction in human cells. Proc Natl Acad Sci U S A. Jan 2;121(1):e2315865120.

Greigert V, Saraav I, Son J, Zhu Y, Dayao D, Antia A, Tzipori S, Witola WH, Stappenbeck TS, Ding S, and Sibley LD. (2024) Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus. Gut Microbes. Jan-Dec;16(1):2297897.

Kawagishi T, Sánchez-Tacuba L, Feng N, Costantini VP, Tan M, Jiang X, Green KY, Vinje J, Ding S#, and Greenberg HB#. (2023) Mucosal and systemic neutralizing antibodies to norovirus induced in infant mice orally inoculated with recombinant rotaviruses. Proc Natl Acad Sci U S A. Feb 28;120(9):e2214421120. # co-corresponding authors

Zhu M, Lv J, Wang W, Guo R, Zhong C, Antia A, Zeng Q, Li J, Liu Q, Zhou J, Zhu X, Fan B, Ding S#, and Li B#. (2023) CMPK2 is a host restriction factor that inhibits infection of multiple coronaviruses in a cell-intrinsic manner. PLOS Biol. Mar 17;21(3):e3002039. # co-corresponding authors

Crawford SE, Ding S, Greenberg HB, and Estes MK. (2022) Fields Virology, 7th Edition, Volume 3: RNA Viruses. Chapter 12: Rotaviruses.

Zhu Y*, Sánchez-Tacuba L*, Hou G*, Kawagishi T, Feng N, Greenberg HB, and Ding S. (2022) A recombinant murine-like rotavirus with Nano-Luciferase expression reveals tissue tropism, replication dynamics, and virus transmission. Front Immunol. doi.org/10.3389/fimmu.2022.911024. * co-first authors

Sánchez-Tacuba L*, Kawagishi T*, Feng N, Jiang B, Ding S#, and Greenberg HB#. (2022) The role of the VP4 attachment protein in rotavirus host range restriction in an in vivo suckling mouse model. J Virol. Jul 12:e0055022. * co-first authors, # co-corresponding authors

Fan B, Peng Q, Song S, Shi D, Zhang X, Guo W, Li Y, Zhou J, Zhu X, Zhao Y, Guo R, He KW, Fan H, Ding S, and Li B. (2022) Nonstructural protein 1 of variant PEDV plays a key role in escaping replication restriction by complement C3. J Virol. Aug 29:e0102422.

Antia A*, Pinski AN*, and Ding S. (2022) Re-examining rotavirus innate immune evasion: potential applications of the reverse genetics system. mBio. Jun 14:e0130822.

Caraballo GI, Rosales R, Viettri M, Ding S, Greenberg HB, and Ludert JE. (2022) The dengue virus non-structural protein 1 (NS1) interacts with the putative epigenetic regulator DIDO1 to promote flavivirus replication in mosquito cells. J Virol. Jun 2;e0070422.

Wang A, Wang J, Tao W, Tong J, Hou G, Gao J, Zhang G, Ren X, Li R, Wang D, Zhang K, Pan W, Ding S, Flavell RA, Li HB, and Zhu S. (2022) m6A modifications regulate intestinal immunity and rotavirus infection. eLife. Jan 31;11:e73628.

Son J*, Huang S*, Zeng Q*, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Harastani HH, Chen L, Gomez Castro MF, Zhao Y, Kohio HP, Hou G, Fan B, Niu B, Guo R, Rothlauf PW, Bailey AL, Wang X, Shi PY, Martinez ED, Whelan SPJ, Diamond MS, Boon ACM, Li B#, and Ding S#. (2022) JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis. mBio. Jan 18;e0337721. * co-first authors, # co-corresponding authors

Park SB, Irvin P, Hu Z, Khan M, Hu X, Zeng Q, Chen C, Leek M, Zang R, Case JB, Zheng W, Ding S, and Liang TJ. (2022) Targeting the fusion process of SARS-CoV-2 infection by small molecule inhibitors. mBio. Jan 11:e0323821.

Hou G, Zeng Q, Matthijnssens J, Greenberg HB, and Ding S#. (2021) Rotavirus NSP1 contributes to intestinal viral replication, pathogenesis, and transmission. mBio. Dec 21;12(6):e0320821.

Antia A, Alvarado DM, Ding S, and Ciorba MA. (2021). Adding Fuel to The Fire? A Role of Intraepithelial Lymphocytes in Enteric Immune Responses to SARS-CoV-2 Infection. Gastroenterology. Dec 22;S0016-5085(21)04120-2.

Song Y*, Hou G*, Diep J, Ooi YS, Akopyants NS, Beverley SM, Carette JE, Greenberg HB, and Ding S. (2021) Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation. Nucleic Acids Res. Nov 17: gkab1070. * co-first authors

Alvarado DM, Son J, Thrackray LB, Gomez Castro MF, Prasad S, Cui X, Sonnek NM, Diamond MS, Ding S, and Ciorba MA. (2021) Mesalamine Reduces Intestinal ACE2 Expression Without Modifying SARS-CoV-2 Infection or Disease Severity in Mice. Inflamm Bowel Dis. Nov 28: izab274.

Ding S and Greenberg HB. (2021) Perspectives for the optimization and utility of the rotavirus reverse genetics system. Virus Res. Oct 2;303:198500.

Lu Q*, Zhao S*, Liu J*, Gomez Castro MF, Dong J, Laurent-Rolle M, Tang H, Son J, Zhang Z, Karakousi T, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, McCune BT, Chen RT, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov S, Stapleford KA, Diamond MS, Aifantis I, Cresswell P, Liu Y, Ding S#, Xie Q#, and Wang J#. (2021) SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2. Immunity. Jun 8;54(6):1304-1319.e9. * co-first authors, # co-corresponding authors

Zang R, Case JB, Yutuc E, Ma X, Shen S, Gomez Castro MF, Liu Z, Zeng Q, Zhao H, Son J, Rothlauf PW, Kreutzberger AJB, Hou G, Zhang H, Bose S, Wang X, Vahey MD, Mani K, Griffiths WJ, Kirchhausen T, Fremont DH, Guo H, Diwan A, Wang Y, Diamond MS, Whelan SPJ, and Ding S. (2020) Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. Proc Natl Acad Sci U S A. Dec 15; 117(50):32105-32113.

Zang R*, Gomez Castro MF*, McCune BT, Zeng Q, Rothlauf PW, Sonnek NM, Liu Z, Brulois KF, Wang X, Greenberg HB, Diamond MS, Ciorba MA, Whelan SPJ, Ding S. (2020) TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Sci Immunol. May 13;5(47):eabc3582.

Sánchez-Tacuba L, Feng N, Meade NJ, Mellits KH, Jais PH, Yasukawa LL, Resch TK, Jiang B, Lopez S, Ding S#, and Greenberg HB#. (2020) An optimized reverse genetics system suitable for efficient recovery of simian, human and murine-like rotaviruses. J Virol. Aug 5. doi: 10.1128/JVI.01294-20. # co-corresponding authors

Case JB*, Rothlauf PW*, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet L, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe GK, Henderson JP, Miersch S, Ustav M, Sidhu S, Virgin HW, Wang D, Ding S, Corti D, Theel ES, Fremont DH, Diamond MS, and Whelan SPJ. (2020) Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2. Cell Host Microbe. Sep 9;28(3):475-485.e5.

Ding S#, T. Jake Liang#. (2020) Is SARS-CoV-2 Also an Enteric Pathogen with Potential Fecal-Oral Transmission: A COVID-19 Virological and Clinical Review. Gastroenterology. doi: 10.1053/j.gastro.2020.04.052. # co-corresponding authors

Ding S*#, Song Y*, Brulois KF, Pan J, Co JY, Ren L, Feng N, Yasukawa LL, Sanchez-Tacuba L, Wosen JE, Mellins ED, Monack DM, Amieva MR, Kuo CJ, Butcher EC, and Greenberg HB#. (2020) Retinoic acid and lymphotoxin signaling promote differentiation of human intestinal M cells. Gastroenterology. Jul; 159(1):214-226.e1. * co-first authors, # co-corresponding authors

Song Y*, Feng N*, Sanchez-Tacuba L, Yasukawa LL, Ren L, Silverman RH, Ding S#, and Greenberg HB#. Reverse genetics reveals a role of the rotavirus VP3 phosphodiesterase activity in inhibiting RNase L signaling and contributing to intestinal viral replication in vivo. (2020) J Virol. * co-first authors, # co-corresponding authors

Ren L*, Ding S*#, Song Y*, Li B*, Co J, Ramanathan M, Amieva MR, Khavari PA, and Greenberg HB#. (2019) Profiling of rotavirus 3’UTR binding proteins reveals ATP synthase subunit ATP5B as a novel host factor that supports late stage virus replication. J Biol. Chem. * co-first authors, # co-corresponding authors

Feng N, Hu L, Ding S, Ramani S, McNeal M, Yasukawa LL, Song Y, Prasad BVV, and Greenberg HB. (2019) Human VP8* antibodies neutralize rotavirus selectively in human intestinal epithelial cells. J Clin Invest.

Ding S#, Zhu S, Ren L, Feng N, Song Y, Ge X, Li B, Flavell RA, and Greenberg HB#. (2018) Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells. eLife. # co-corresponding authors

Ding S, Diep J, Feng N, Ren L, Li B, Ooi YS, Wang X, Brulois KF, Yasukawa LL, Li X, Kuo CJ, Solomon DA, Carette JE, and Greenberg HB. (2018) STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nature Comm.

Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin X, Wong J, Ding S, Seki E, Schnabl B, Hevener A, Greenberg HB, Kisseleva T, and Karin M. (2018) New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature.

Zhu S*, Ding S*, Wang P, Wei Z, Yang Y, Li H, Pan W, Wang G, Lei X, Yu H, Palm NW, Zoete M, Zheng Y, Zhao J, Chen H, Zhao Y, Jurado K, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, and Flavell RA. (2017) Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. * co-first authors

Li B*, Ding S*#, Feng N, Mooney N, Ooi YS, Ren L, Diep J, Kelly MR, Yasukawa LL, Patton JT, Yamazaki H, Shirao T, Jackson PK, and Greenberg HB#. (2017) Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis. PNAS. * co-first authors; # co-corresponding authors 

Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, and Greenberg HB. (2016) Comparative proteomics reveals strain-specific β-TrCP degradation via rotavirus NSP1 hijacking a host Cullin-3-Rbx1 complex. PLoS Pathog.

Ding S, Khoury-Hanold W, Iwasaki A, and Robek MD. (2014) Epigenetic reprogramming of the type III IFN response potentiates antiviral activity and suppresses tumor growth. PLoS Biol.

Bolen CR.*, Ding S*, Robek MD, and Kleinstein SH. (2014) Dynamic expression profiling of Type I and Type III Interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression. Hepatology. * co-first authors

For a full list of publications, please visit: https://www.ncbi.nlm.nih.gov/myncbi/1B5hQWh5ef7Mwi/bibliography/public/