Welcome to the Ding lab!

We are broadly interested in studying enteric virus-host interactions. We investigate the interface of rotavirus and SARS-CoV-2 replication and pathogenesis, host mucosal immune responses, and intestinal epithelial cell biology.

Research Areas

  • Molecular mechanisms of rotavirus replication and pathogenesis
  • Rotavirus-host interactions
  • Innate immune signaling in the intestinal epithelium
  • Gastrointestinal SARS-CoV-2 infection and diarrhea development

Research Tools

  • Rotavirus reverse genetics system
  • Genome-wide CRISPR-Cas9 screen
  • Virus-host protein interactome
  • Viral RNA binding protein interactome
  • Interferon-stimulated gene screen
  • 2D and 3D human small intestinal enteroid cultures
  • Live-cell imaging
  • Knockout and conditional knockout neonatal mouse models

These posters are meant to show that racial justice and support for marginalized communities cannot be separated from the practice of science. We must actively work to recognize the obstacles that scientists (and potential scientists) from marginalized communities face, and dismantle structures of power that prevent them from succeeding. We must also consider the effects of our research and research choices on marginalized communities. Please see https://sammykatta.com/diversity for more!