Welcome to the Ding lab!

We are interested in studying how rotavirus, a medically important virus that causes diarrhea and vomiting in young children, interacts with the host small intestinal epithelial cells.



Our Research Areas

(1) Molecular mechanisms of rotavirus replication and pathogensis

(2) Virus-host interactions

(3) Innate immune signaling in the intestinal epithelium

Our Research Tools

Rotavirus reverse genetics system

Genome-wide CRISPR-Cas9 screen

Virus-host protein interactome

Viral RNA binding protein interactome

Interferon-stimulated gene screen

Human intestinal enteroids

Knockout and conditional knockout mouse models

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